Kaiser hosts a series of complimentary webinar presentations which demonstrate Raman Spectroscopy-based solutions. Hear from real customers and their success stories using Kaiser Raman analyzers and instruments. Examples of Research Raman, Analytical Raman, Process Raman, In Situ Raman, Industrial Raman, Remote Raman, and Raman Imaging and Microscopy are available during these sessions. We invite you to register for an upcoming webinar of interest, or view previous archives. Kaiser Webinar Archives are available in the sidebar -- see what you've been missing!
Real Customers - Their Applications, Raman Solutions
Raman Analysis of Dynamic Solids during Pharmaceutical Process Development & Manufacturing
In numerous pharmaceutical manufacturing processes, PAT is required to operate in fast moving, complex environments where both physical and chemical properties are set to a range of values with tight tolerances. In these situations, the ideal set of online tools would measure all critical process parameters as close as possible to real-time – to correct for process deviations as well as for real-time process optimization.
In these situations, most online and/or at-line analytical tools consist of one or more of the following traits: the need to pull samples, destructive testing, lack of specificity, overcomplexity of signal, lack of sterility, analysis post-batch, cross-scale model transferability issues, etc. While Raman spectroscopy has made inroads as an effective tool in each of these problematic areas (in both PD and manufacturing), in some cases, the lack of signal-to-noise for the required measurement frequency has limited the scope of the measurement.
In this webinar, we will discuss the ins-and-outs of sampling optimization as well as the advantages of utilizing large volumetric Raman technology to analyze heterogenous pharmaceutical solids. In addition, we will present work that has utilized large volumetric Raman analysis to measure properties in both batch and continuous drug substance processes.
AIR DATE: April 7, 2020
Name: Dr. Sean Gilliam
Title: Senior Applications Scientist
Company: Kaiser Optical Systems, Inc.
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