Products  Kaiser Raman analyzers   Kaiser Raman Hybrid Rxn analyzer

Kaiser Raman Hybrid Rxn analyzer suite

Robust solids analysis packaged in a versatile Raman analyzer

The Kaiser Raman Hybrid Rxn analyzer is our most advanced and flexible solid phase analyzer. It features hybrid (micron and mm) probe capability, high spectral resolution, transportability, and calibration transfer between analyzers. When combined with Kaiser’s phase-optimized sampling probes, it adeptly performs both traditional small spot Raman sampling and wide area Raman sampling needed for robust solids analysis.

Whether you need cart-portable raw materials identification, bench-top methods development in a lab, reaction monitoring in a pilot plant, process control development in a manufacturing environment, or a dedicated quality control analyzer—the robust Kaiser Raman Hybrid Rxn analyzer is up to the task.

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Additional Components

PhAT Probe

PhAT probe

Easy-to-use calibration protocol for qualitative and quantitative spectral analysis

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Pilot-E Probe

Kaiser Raman Pilot-E probe

Process probe compatible for direct insertion

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Kaiser Calibration Accessory product

Calibration Accessory

Easy-to-use calibration protocol for qualitative and quantitative spectral analysis

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  • Enables the use of a single base unit to support 1 PhAT probe and 1 non-PhAT probe
  • mm to micron sampling
  • Up to 6mm spot size measurement
  • Multi-analyzer calibration transfer demonstrated
  • Low cost of ownership
  • Easy to install
  • No consumables
  • Minimal maintenance requirements / analyzer technician times
  • Robust data modeling based on Raman spectroscopy
  • Scale-up and Pilot-plant compatible

Field of application

Life Sciences
Pharmaceutical Formulations Development: Blending, Granulations, Drying
Pharmaceutical API Development: Reaction Chemistry, Yield
Crystallization and Polymorph
PAT / QbD Applications
GLP/GMP compatible

Polymer Blending
Extrusion Monitoring
Catalysis Investigations

Food & Beverage
Dairy solids, quality
Meat and fish composition

Features and Specifications

Measuring principle

Laser wavelength
785 nm

Spectral coverage
175-1890 cm-1 (λ=785 nm)

1 PhAT channel, 1 alternative channel (non-PhAT)

Rxn2: 15°C – 30°C (operating); -15°C to +50°C (storage)
Rxn4 Base model: +5°C to +35°C (operating); -15°C to +50°C (storage)
NEMA 4x enclosure model: 5°C to +50°C (operating); -15°C to +50°C (storage)

Relative humidity
20–80% RH, noncondensing

Input voltage
Rxn2/Rxn4 base model: 100-240 V, 50-60 Hz, ±10%
NEMA 4x enclosure model: 115 V ±10%, 60 Hz; or 230 V ± 10%, 50/60 Hz

Power consumption
Base Model: Maximum, 400 W; Startup, 250 W (typical); Operation, 120 W (typical)
NEMA 4x enclosure model: 1560 Watts

Warm up time
Rxn2 and Rxn4 base models: 120 Minutes
NEMA 4x enclosure model: 240 minutes

Unit dimensions (mm)
Rxn2 benchtop model: 279 x 592 x 483
Rxn2 cart model: 710 x 760 x 1015
Rxn4 base model: 483 x 556 x 267
NEMA 4x enclosure model: 1175 x 1480 x 826

Weight (kg)
Rxn2 base model: 32
Rxn2 cart mounted: 93
Rxn4 base model: 28.5
NEMA 4x enclosure model: 185.5

Sampling probe compatibility
Solids: PhAT probe
Liquids: RamanRxn, bIO-LAB, bIO-PRO, SUB-Optic system, WetHead, Pilot-E

Connection Interface

(contact us for other options)

North American, ATEX (contact us for other options)

Packaging options
Rxn2, wheeled cart option
Rxn4 base model, 19″ rack compatible
Rxn4 base model, 19″ rack package
NEMA 4x enclosure model, 110 or 230 VAC, with trolley
NEMA 4x enclosure model, 110 or 230 VAC, with stand

Documents/ Manuals/Software


Application Notes:


Feb 24, 2020 – Sartorius Introduces BioPAT® Spectro QbD Tool

The BioPAT® Spectro offers access to Raman spectroscopy analysis in high throughput process development, supporting faster Raman model building and accelerating scale-up into commercial manufacturing.

Read the full story

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10/23/2020 10:00 AM EST

Please join Dejan Arzenšek, Principal Scientist at Novartis and Maryann Cuellar from Kaiser Optical Systems, Inc. as they team up to discuss PAT tool mapping for enabling integrated DSP in continuous biomanufacturing, followed by an additional perspective on the biopharma industry.  The webinar is presented as part of  the BioPharma Asia Magazine webinar series.

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