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Kaiser Raman Rxn2 analyzer

The bridge from laboratory analysis to the process environment

The Kaiser Raman Rxn2 analyzer adeptly harnesses the power of Raman spectroscopy while serving as an ideal bridge from lab-to-process. Designed for use in analytical laboratories with model transfer capabilities, the Raman Rxn2 is heavily relied on for routine sample identification, support of R&D projects, early process development, and scale-up settings for in situ analysis.

Combined with our high-performance sampling probes, the Raman Rxn2 delivers high resolution performance for real-time, in-process measurement and control. It features unique self-monitoring, diagnostics, and self-calibration to ensure the validity of each measurement. Available as a benchtop or on a mobile wheeled cart, the Raman Rxn2 offers location convenience and portability for process development laboratories.

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Additional Components

Kaiser SUB Optic

SUB-Optic probe system

Developed according to industry standards for single-use sensors

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Kaiser Raman bIO-PRO Probe

bIO-PRO Raman probe

Compatible with bioprocess industry standard housings for 25mm side ports

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Kaiser Raman PhAT Probe front lens view

PhAT probe

Robust probe for solids and semi-solids measurement

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Benefits

  • Reliable real-time, in situ measurements
  • Intuitive, embedded control software via touchscreen or remote interface
  • Convenience of a single base unit supporting up to four probes
  • Sequential operation for fast analysis per channel and programmable channel interrogation
  • Converts acquired Raman spectra into process knowledge using built-in multivariate predictors
  • Suitable for outputs into hazardous area/classified environments
  • cGLP/cGMP compatible

Field of application

Life Sciences
Pharmaceutical: reaction chemistry, yield crystallization, polymorph, blending, drying, granulations
Biopharmaceutical: bioprocess monitoring and control, PAT/QbD applications, cell culture, fermentation, downstream operations, cGLP/cGMP compatible

Chemical
Polymerization, extrusion monitoring, polymer blending, catalysis investigation

Food & Beverage
Zonal heterogeneity, fermentation

Features and specifications

Measuring principle
Raman

Laser wavelength
532 nm, 785 nm, 1000 nm

Spectral coverage
150-4350 cm-1 ( λ=532 nm); 150-3425 cm-1 (λ=785 nm); 200-2400 cm-1 (λ=1000 nm)

Channels
Up to four channels

Temperature
15°C – 30°C (operating); -15°C to +50°C (storage)

Relative humidity
20-80%, RH noncondensing

Input voltage
100-240 V, 50-60 Hz, ±10%

Power consumption
Maximum: 400 W
Start-up: 250 W (typical)
Running: 120 W (typical)

Warm up time
120 minutes

Unit dimensions (width x height x depth in mm)
Benchtop model: 279 x 483 x 592
Cart model: 685 x 1022 (to tabletop) x 753

Weight (kg)
Benchtop model: 32 (non-embedded Rxn2: 31)
Cart model: 93

 

Sampling probe compatibility
Solids: RamanRxn (with optics)
Liquids: RamanRxn (with optics), bIO-PRO (standard & KS model), WetHead, Pilot-E
Gases: AirHead

Connection interface
OPC
Modbus

(contact us for other options)

Hazardous area certifications
ATEX, North American, IECEx

Installation options
Benchtop (standard) or mobile wheeled cart

Documents/ Manuals/Software

Brochures:

Application Notes:

bIO-PRO KS 785 Installed Lab with operator

NEWS

2020 Pharma Innovation Award

Our Kaiser Raman bIO-PRO, KS bioprocessing probe was recently selected as a 2020 Pharma Innovation Award winner by Pharma Manufacturing Magazine!

The Kaiser Raman bIO-PRO, KS probe provides fast, accurate measurement of key bioprocess variables from lab-to-process. It is an exciting advancement in our already well-established Kaiser Raman bioprocess product portfolio.

Read award announcement

Two employee with proper PPE and stainless steel Bio Reactor_resized

SUCCESS STORIES

Advanced bioprocess control

Learn how Kaiser Raman technology helped Nicro eliminate time-consuming offline sampling in favor of real-time monitoring of critical parameters in fermentation processes.

Read success story

2021 Coblentz Society William Wright award recipient, Dr. Ian Lewis

NEWS

2021 Williams-Wright Award

Dr. Ian R. Lewis, Director of Marketing at Kaiser Optical Systems, has been named the 2021 Williams-Wright Award recipient by The Coblentz Society for his significant contributions to vibrational spectroscopy. The award was presented during the 2021 Pittcon Conference & Expo.

Read award announcement