Products  Kaiser Raman analyzers   Kaiser Raman Rxn4 process analyzer

Kaiser Raman Rxn4 process analyzer

Rugged, reliable Raman analyzer ensuring 24/7 process and quality monitoring

The Kaiser Raman Rxn4 analyzer is ideal for the manufacturing or process environment, offering a unique self-monitoring system to ensure the validity of each measurement. When combined with Kaiser’s phase-optimized sampling probes, the Kaiser Raman Rxn4 provides high-resolution performance for in situ, real-time process measurement and control.

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Additional Components

WetHead Probe

Kaiser Raman WetHead probe

Liquids probe compatible with installations in hazardous areas and classified environments

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Pilot-E Probe

Kaiser Raman Pilot-E probe

Process probe compatible for direct insertion

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Kaiser Calibration Accessory product

Calibration Accessory

Easy-to-use calibration protocol for qualitative and quantitative spectral analysis

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  • Enables the use of a single base unit to support up to 4 probes
  • Direct in situ measurement of process samples
  • Multi-analyzer calibration transfer demonstrated
  • Low cost of ownership
  • Easy to install
  • No consumables
  • Minimal maintenance requirements / analyzer technician times
  • Robust data modeling based on Raman spectroscopy
  • Scale-up and Pilot-plant compatible
  • NEMA, wash down compatible enclosure

Field of application

Life Sciences
Pharmaceutical Formulations Development: Blending, Granulations, Drying
Pharmaceutical API Development: Reaction Chemistry, Yield
Crystallization and Polymorph
PAT / QbD Applications
Biologics / Biomedical
GLP/GMP compatible

Polymer Blending
Extrusion Monitoring
Catalysis Investigations

Food & Beverage

Features and Specifications

Measuring principle

Laser wavelength
532 nm, 785 nm, 1000 nm

Spectral coverage
150-4350 cm-1 ( λ=532 nm); 150-3425 cm-1 (λ=785 nm); 200-2400 cm-1 (λ=1000 nm)

1 channel or 4 channel options available

Base model operating temperatures: +5°C to +35°C (532 nm, 785 nm); +5°C to +30°C (1000 nm)
Base model storage temperatures: -15°C to +50°C (for all wavelengths)
NEMA 4x enclosure model (for all wavelengths): 5°C to +50°C (operating); -15°C to +50°C (storage)

Relative Humidity
20–80% RH, noncondensing

Input Voltage
Base model: 100-240 V, 50-60 Hz, ±10%
NEMA 4x enclosure model: 115 V ±10%, 60 Hz; or 230 V ± 10%, 50/60 Hz

Power consumption
Base Model: Maximum, 400 W; Startup, 250 W (typical); Operation, 120 W (typical)
NEMA 4x enclosure model: 1560 Watts

Warm up time
Base model: 120 Minutes
NEMA 4x enclosure model: 240 minutes

Unit dimensions (mm)
Base model: 483 x 556 x 267
NEMA 4x enclosure model: 1175 x 1480 x 826

Weight (kg)
Base model: 28.5
NEMA 4x enclosure model: 185.5
Rxn4, non-embedded: 61 lbs
Rxn4, embedded: 63 lbs

Sampling probe compatibility
Solids: Kaiser non-contact optics
Liquids: RamanRxn, bIO-LAB, bIO-PRO, SUB-Optic system, WetHead, Pilot-E
Gases: AirHead (532 nm only)

Connection Interface

(contact us for other options)

North American, ATEX (contact us for other options)

Packaging options
Base model, 19″ rack compatible
Base model, 19″ rack package
NEMA 4x enclosure model, 110 or 230 VAC, with trolley
NEMA 4x enclosure model, 110 or 230 VAC, with stand

Documents/ Manuals/Software


Application Notes:


Feb 24, 2020 – Sartorius Introduces BioPAT® Spectro QbD Tool

The BioPAT® Spectro offers access to Raman spectroscopy analysis in high throughput process development, supporting faster Raman model building and accelerating scale-up into commercial manufacturing.

Read the full story

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10/23/2020 10:00 AM EST

Please join Dejan Arzenšek, Principal Scientist at Novartis and Maryann Cuellar from Kaiser Optical Systems, Inc. as they team up to discuss PAT tool mapping for enabling integrated DSP in continuous biomanufacturing, followed by an additional perspective on the biopharma industry.  The webinar is presented as part of  the BioPharma Asia Magazine webinar series.

Register Today!