Kaiser Raman bIO-PRO, KS probe
The Kaiser Raman bIO-PRO, KS bioprocess probe has been adapted to fit the BioPAT® Spectro platform by Sartorius
The recent union between Kaiser Raman analyzers equipped with bioprocess probe technology and the BioPAT® Spectro platform by Sartorius offers the market an ideal interface to high throughput development through single-use commercial manufacturing. Kaiser Raman’s bioprocessing probe technology has been adapted to fit Sartorius’s BioPAT® Spectro platform, utilizing the same Kaiser Raman probe design for Ambr® 15, Ambr® 250, & Biostat STR® bioreactors. Compatibility with BioPAT® Spectro from Sartorius is an exciting advancement in the already well-established Kaiser Raman bioprocessing product portfolio.
Additional Components
BioPAT® Spectro by Sartorius
Find out about Kaiser Raman's exciting collaboration with Sartorius in bioprocessing
Benefits
- Enables faster, easier, and more robust model building via integration with Ambr® 15 and Ambr® 250
- Allows high throughput process development which supports QbD
- Provides a more efficient transfer to Biostat STR® for single-use manufacturing
- Offers a scale-independent interface from 15 ml in the laboratory to 2000 L in the production suite
- Requires no probe cleaning, sterilization, or frequent maintenance due to non-contact sampling
Field of Application
- Cell culture: glucose, lactate, amino acids, cell density, titer, and more
Features and Specifications
Analyzer
Ambr®: Kaiser Raman Rxn2 single-channel
Biostat STR®: Embedded or non-embedded Kaiser Raman Rxn2 or Rxn4 analyzers
Installation configuration
Ambr®: Benchtop
Biostat STR®: Benchtop or mobile wheeled cart (Raman Rxn2); rack mounted or NEMA 4x enclosure (Raman Rxn4)
Spectral coverage
150-3425 cm-1 (λ=785 nm)
Laser wavelength
785 nm
Maximum laser power into probe
<499 mW
Probe configuration software
Ambr®: Single-channel
Biostat STR®: Up to four channels
Software
Raman RunTime v6.2+
User interface
Touch screen starter kit
Fiber optic cable
Ambr®: 5m EO to EO fiber cable
Biostat STR®: EO to EO fiber cable (standard or custom length); or FC to EO fiber converter(s) for non-embedded systems
Accessories
Kaiser Raman probe calibration accessories
Ambr®: Ambr® flow cell light shield (sold by Kaiser)
Biostat STR®: SIMCA-Q v16 predictor (available for purchase in Raman RunTime v6.2+ software); BioPAT® Spectro Support (locking mechanism from Sartorius)
Documents/ Manuals/Software
Data Sheet:
Brochures:
Kaiser Raman Probes Brochure
Robust optical measurement of chemical composition
Kaiser Raman Analyzers Brochure
Robust optical measurement of chemical composition
Kaiser Raman in Bioprocessing Brochure
Scalable in situ bioprocess monitoring enabling advanced process control
Application Notes:
EVENTS
IFPAC-2021 (February 28 – March 5, 2021)
Join us for our three virtual presentations at IFPAC-2021:
March 1st at 1-5:30 PM EST – Smart‐Raman spectroscopy for automated monitoring and control of industrial processes
March 2nd at 1-5:30 PM EST – Tips and tricks to make process Raman spectroscopy a success
March 4th at 7:45-11:00 AM EST – Raman spectroscopy for automated monitoring and control of bioprocesses
NEWS
2020 Pharma Innovation Award
Our Kaiser Raman bIO-PRO, KS bioprocessing probe was recently selected as a 2020 Pharma Innovation Award winner by Pharma Manufacturing Magazine!
The Kaiser Raman bIO-PRO, KS probe provides fast, accurate measurement of key bioprocess variables from lab-to-process. It is an exciting advancement in our already well-established Kaiser Raman bioprocess product portfolio.
EVENTS
2021 Pittcon Conference & Expo (March 8-12, 2021)
Join us during our two virtual presentations at the 2021 Pittcon Conference & Expo:
March 8th at 1:30 PM EST – The Role of Process Raman Spectroscopy in Chemical and Polymer Applications
March 12 at 9:30 AM EST – Analytical Model Development for Raman Spectroscopy of Pharmaceutical Solids Processing and Upstream Bioprocessing