Products  Kaiser Raman Probes   Kaiser Raman Pilot E-Probe

Kaiser Raman Pilot-E Probe

Offering sampling versatility in the lab and reduced cost for the process environment

The single cable design of the Kaiser Raman Pilot-E probe simplifies installation, eliminates risk scenarios where the interlock is separate from the laser excitation, and minimizes installed cost for long fiber runs in the process environment. All Pilot probes utilize a hybrid electro/optical fiber cable assembly to carry the analytical signal and the safety interlock in a single easy to install cable.  Kaiser Raman Pilot-E probes are ideal for:

  • Pharmaceutical manufacturing facilities in glass-lined reactors as part of a Quality-by-Design (QbD) solution using Process Analytical Technology (PAT) analyzers (does not require reactor modification)
  • Chemical facilities to measure batch or continuous flow production

For direct measurements in cryogenic fluids, an optimized cryogenic version of the Pilot-E probe is available.

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Additional Components


Kaiser Raman Rxn4

Process Raman analyzer ensuring 24/7 process and quality monitoring

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Kaiser Calibration Accessory product

Calibration Accessory

Easy-to-use calibration protocol for qualitative and quantitative spectral analysis

More information

PhAT Probe

PhAT probe

Easy-to-use calibration protocol for qualitative and quantitative spectral analysis

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  • Probe constructed to individual site requirements
  • Sealed probe design
  • Integrated “laser on” indicator
  • One in/one out fiber optics
  • Hazardous area certified: North America, ATEX, International

Field of Application

  • Chemical: reaction monitoring, blending
  • Polymer: polymerization reaction monitoring, polymer blending
  • Pharmaceutical: API reaction monitoring, crystallization, polymorph, drug substance production unit operation
  • Oil & Gas: fuel blending, fuel characterization

Features and Specifications

Measuring principle

Laser wavelength
532 nm, 785 nm, 1000 nm

Spectral coverage
175-4350 cm-1 (532 nm)
150-3425 cm-1 (785 nm),
200-2400 cm-1 (1000 nm)

Maximum laser power into probe head
≤499 mW

Sample Interface
SS 316L: –30° to 120°C
Alloy C276: –30° to 150°C
Titanium: –30° to 150°C

Flange: up to 305 diameter, ANSI B 16.5 or DIN

Cryogenic compatible version available upon request

Relative Humidity
Up to 95%, non-condensing

SS 316L: Up to 370 psi
Alloy C276: up to 650 psi
Titanium: up to 150 psi

Body and wetted materials
Body: Alloy C276
(SS 316L and titanium options available, contact us for more information)

Window: High-purity sapphire

Fiber optic cable
Design: PVC jacketed, proprietary construction
Connections: proprietary electro-optic
Temperature: –40 to 80°C
Length: 5000 mm (16.4 feet) standard, custom lengths available
Minimum bend radius: 152.4 mm (6 inches)

Length (mm)
Contact Kaiser for more information
(lengths from 152 mm to 4,572 mm have been previous constructed)

Diameter (mm)
From 25-51

Documents/ Manuals/Software


Application Notes:


Feb 24, 2020 – Sartorius Introduces BioPAT® Spectro QbD Tool

The BioPAT® Spectro offers access to Raman spectroscopy analysis in high throughput process development, supporting faster Raman model building and accelerating scale-up into commercial manufacturing.

Read the full story

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10/23/2020 10:00 AM EST

Please join Dejan Arzenšek, Principal Scientist at Novartis and Maryann Cuellar from Kaiser Optical Systems, Inc. as they team up to discuss PAT tool mapping for enabling integrated DSP in continuous biomanufacturing, followed by an additional perspective on the biopharma industry.  The webinar is presented as part of  the BioPharma Asia Magazine webinar series.

Register Today!